verezdoВестник репродуктивного здоровьяBulletin of Reproductive Health2075-65692310-421XEndocrinology Research Centre (Moscow)10.14341/brh20083-413-24verezdo-8535Research ArticleСтатьиArticlesТерапевтические возможности метформина при восстановлении фертильности у пациенток с синдромом поликистозных яичниковTerapevticheskie vozmozhnosti metformina pri vosstanovlenii fertil'nosti u patsientok s sindromom polikistoznykh yaichnikovЧеботниковаТ ВChebotnikovaT V-СемичеваТ ВSemichevaT V-ФГУ Эндокринологический научный центр20081512200803-4№3-4 (2008)1324Copyright © Чеботникова Т.В., Семичева Т.В., 20082008Чеботникова Т.В., Семичева Т.В.Chebotnikova T.V., Semicheva T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vrz-endojournals.ru/jour/article/view/8535

СПКя – клинический синдром, характерными клиническими признаками которого являются гиперандрогения, нарушение овуляции и увеличение объема яичников за счет множественных фолликулов по периферии. Дефиниция СПКя остается до сих пор дискуссионным вопросом – клинические признаки синдрома неспецифичны и довольно распространены в популяции среди практически здоровых женщин. СПКя фактически является гетерогенным состоянием, поэтому обсуждение диагностических критериев остается ключевым вопросом для понимания синдрома. К настоящему времени были предложены и приняты два варианта диагностических критериев. В апреле 1990 г – критерии Национального Института Здоровья (NIH) и Национального Института Здоровья ребенка и Развития человека (NICHD) США [1]. После длительного обсуждения в Роттердаме в мае 2003 г приняты действующие в настоящее время диагностические критерии Европейского Общества Репродукции Человека и Эмбриологии (ESHRE) и Американского Общества Репродуктивной Медицины (ASRM) [2]. Роттердамские критерии значительно расширили количество клинических фенотипов СПКя.

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The authors declare that there are no conflicts of interest present.