Clinical case of disorder of sex development, 46 XY, SRY+
https://doi.org/10.14341/brh12772
Abstract
People, who born with disorders/differences of sex development (hereinafter -DSD) represent a special cohort of patients, because their observation and treatment requires the cooperative work of endocrinologists, gynecologists, surgeons and psychologists. The execution of gonadectomy at a later age is associated with a high risk of development of herminous tumors, and untimely initiated hormone replacement therapy determines incorrect development of secondary sexual characteristics and growth parameters. The goal of specialists is to help such patients realize their reproductive plans and ensure a full life in society. The right management tactics are largely determined by the level of awareness of the patient and his/her parents. Thus, one of the most important duties of doctors is to provide them with up-to-date data on these conditions.
We present a clinical case of disorders/differences of sex development with karyotype 46 XY, positive SRY gene, which reflects the importance of concepts of international consensus in patients with this condition.
About the Authors
V. D. Ankina
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Vlada D. Ankina
11 Dm. Ulyanova street, 117036 Moscow
Competing Interests:
none
E. V. Morozova
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Elena V. Morozova – MD
Moscow
Competing Interests:
none
A. F. Vesnina
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Anna F. Vesnina - PhD.
Moscow
Competing Interests:
none
L. V. Savel’eva
Endocrinology Research Centre
Russian Federation
Competing Interests:
Russian Federation
Larisa V. Savelyeva - MD, PhD.
Moscow
Competing Interests:
none
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For citations:
Ankina V.D., Morozova E.V., Vesnina A.F., Savel’eva L.V. Clinical case of disorder of sex development, 46 XY, SRY+. Bulletin of Reproductive Health. 2025;4(3):47-52. (In Russ.) https://doi.org/10.14341/brh12772
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