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Possibilities of non-hormonal therapy in the correction of manifestations of climacteric syndrome

https://doi.org/10.14341/brh12775

Abstract

Vasomotor symptoms during the menopausal transition occur in 80% of women and can last for years, which seriously reduces the quality of life. Typical complaints of patients include hot flashes, increased sweating, and sleep disorders. Treatment and correction of menopausal transition problems is an important task for an obstetrician-gynecologist. Today, menopausal hormone therapy is the gold standard in stopping hot flashes and preventing osteoporosis, but it has serious limitations and contraindications. For those categories of women who cannot or do not want to take hormonal drugs due to personal preferences, non-hormonal alternative methods should be offered. The article provides an overview of possible options for drug and non-drug interventions, and discusses evidence of the effectiveness and safety of alternative means, including dietary correction using a complex of herbal components and vitamins Estrovel in order to prevent the pathological course of menopause and prevent age-associated conditions. The literature search was carried out in Russian (eLibrary, CyberLeninka.ru) and international (PubMed, Cochrane Library) databases. Free access to the full text of publications was preferred. The selection of sources was prioritized by the period from 2018 to 2025, however, the list of references includes works dated earlier.

About the Authors

E. N. Andreeva
Endocrinology Research Centre Russia; Russian University of medicine
Russian Federation

Elena N. Andreeva - MD, PhD, professor.

Moscow


Competing Interests:

none



Yu. S. Absatarova
Endocrinology Research Centre Russia
Russian Federation

Yulia S. Absatarova - MD, PhD.

11 Dm. Ulyanova street, 117036 Moscow


Competing Interests:

none



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For citations:


Andreeva E.N., Absatarova Yu.S. Possibilities of non-hormonal therapy in the correction of manifestations of climacteric syndrome. Bulletin of Reproductive Health. 2025;4(3):20-27. (In Russ.) https://doi.org/10.14341/brh12775

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