Molochnaya zheleza kak svoeobraznyy intrakrinnyy organ
https://doi.org/10.14341/brh2009139-44
Abstract
В статье рассмотрены особенности молочной железы как интракринного органа, представлены пути синтеза и метаболизма эстрогенов в ее ткани. Приведены эпидемиологические данные по заболеваемости раком молочных желез (РМЖ) на фоне заместительной гормональной терапии (ЗГТ), рассмотрены факторы риска его развития. Подробно представлены пути метаболизма эстрогенов и свойства их гидроксиметаболитов. Приведены данные собственных исследований по определению уровней основных гидроксиметаболитов эстрогенов у женщин в постменопаузе группы низкого риска развития РМЖ и не принимающие препараты ЗГТ, а также их взаимосвязь с основными факторами риска РМЖ.
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Review
For citations:
Smetnik V.P., Konovalova V.N. Molochnaya zheleza kak svoeobraznyy intrakrinnyy organ. Bulletin of Reproductive Health. 2009;(1):39-44. (In Russ.) https://doi.org/10.14341/brh2009139-44
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