Article is devoted an actual problem of gynecology – to an endometriosis which meets on the average at 12-50 % fertility women with chronic pelvic pain and/or barreness and at 5-35 % of women of reproductive age.Authors states results of researches of last years directed on working out of the new approach to treatment of patients with an endometriosis – complex therapy (antiviral preparations, hormonal therapy and immunomodulators) which application f or patients with an endometriosis extends time of remission of disease and increases frequency of approach of pregnancy.

According to various authors myoma remains one of the most common diseases in women of reproductive age and is25-50% of all women over 30 years. Article contains a summary of interventional and modern method of treatment of uterine myoma by the uterine artery embolization. Detailed operation method reflected preand post-operative management of patients. Generalized international experience by the embolization on the impact on fertility and reproduction.

Today about 80 million women prevent unintended pregnancies using oral contraceptives all over the world. Oral contraceptives have been the most investigated medicines arriving on the market. The data about their potential benefits and risks for health are updated regularly, and thе tendency, maintenance is expected. Oral contraceptives are considered as the main large achievement in reproductive medicine because they provide essential health benefits, confirmed numerous researches; serious adverse effects were observed extremely seldom. Routine risk-factor revealing in potential users of oral contraceptives significantly decreases the conditions frequency of serious adverse effects.

Polycystic ovary syndrome (PCOS) – a polymorphic disease with extremely variable clinical presentation and different phenotypes found in 5-10% of women of reproductive age. During the life of women with PCOS in 10-fold increased risk of developing type 2 diabetes, 7 times – hypertension and coronary heart disease, including myocardial infarction, more than2-fold increased risk of developing ovarian cancer, endometrial, breast cancer. Women with PCOS and if they have insulin resistance, central obesity, dyslipidemia, have the greatest risk of developing diabetes and cardiovascular disease. The use of metformin is potentially an effective method to overcome insulin resistance, improve hormonal, biochemical parameters and a possible reduction in cardiovascular risk in PCOS.